Article
Rifampicin resistance and its fitness cost in Enterococcus faecium.
The Journal of antimicrobial chemotherapy - 1 Feb 2004
Enne V I, Delsol A A, Roe J M, Bennett P M
Abstract excerpt
OBJECTIVES: The genetic basis of rifampicin resistance and the associated fitness cost in Enterococcus faecium were investigated. METHODS: Twelve spontaneous rifampicin-resistant E. faecium mutants were selected from four parent strains recently isolated from porcine faecal material. The DNA sequence of the complete rpoB gene from the parent strains and of nucleotides -189 to +1785 from the mutants was determined...
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