Article
Comprehensive Analysis of the SUL1 Promoter of Saccharomyces cerevisiae.
Genetics - 1 May 2016
Rich Matthew S, Payen Celia, Rubin Alan F, Ong Giang T, Sanchez Monica R, Yachie Nozomu, Dunham Maitreya J, Fields Stanley
Abstract excerpt
In the yeast Saccharomyces cerevisiae, beneficial mutations selected during sulfate-limited growth are typically amplifications of the SUL1 gene, which encodes the high-affinity sulfate transporter, resulting in fitness increases of >35% . Cis-regulatory mutations have not been observed at this locus; however, it is not clear whether this absence is due to a low mutation rate such that these mutations do not...
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