Analysis of fitness costs associated with metronidazole and amoxicillin resistance in Helicobacter pylori.

Abstract excerpt

BACKGROUND: Increasing rates of antibiotic resistance are a major concern for all pathogens, including H. pylori. However, increased resistance often coincides with a decrease in relative fitness of the pathogen in the absence of the antibiotic, raising the possibility that increased resistance can be mitigated for some antibiotics by improved antibiotic husbandry. Therefore, a greater understanding of which...

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