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Article

Impact of plasmid-borne oqxAB on the development of fluoroquinolone resistance and bacterial fitness in Escherichia coli.

The Journal of antimicrobial chemotherapy - 1 May 2017

Wang Jing, Guo Ze-Wen, Zhi Chan-Ping, Yang Tong, Zhao Jing-Jing, Chen Xiao-Jie, Zeng Li, Lv Lu-Chao, Zeng Zhen-Ling, Liu Jian-Hua

Abstract excerpt

Objectives: To investigate the impact of plasmid-borne oqxAB genes on the development of fluoroquinolone resistance, mutations and bacterial fitness in Escherichia coli . Methods: MICs and mutation prevention concentrations were compared among E. coli strain TOP10 and two corresponding transformants harbouring the OqxAB-encoding plasmids. Mutants were selected by serial passages with the 0.5-fold MIC of...

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PMID: 28160469
DOI: 10.1093/jac/dkw576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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