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Article

Analysis of 'driver' and 'passenger' CD8+ T-cell responses against variable viruses.

Proceedings. Biological sciences - 7 Feb 2004

Zafiropoulos Andreas, Barnes Eleanor, Piggott Clive, Klenerman Paul

Abstract excerpt

Variable viruses, such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV), persist despite host immune responses directed against them. Numerous lines of evidence have suggested that antiviral CD8+ T-cell responses are key among these immune responses, but these vary widely in their ability to contain virus. We propose that only a proportion of responses may exert significant antiviral pressure...

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Share to Antigens, Viral
Share to CD8-Positive T-Lymphocytes
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15101418
DOI: 10.1098/rsbl.2003.0088
PMCID: PMC1809984

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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