Article
Viruses selectively mutate their CD8+ T-cell epitopes--a large-scale immunomic analysis.
Bioinformatics (Oxford, England) - 15 Jun 2009
Vider-Shalit Tal, Sarid Ronit, Maman Kobi, Tsaban Lea, Levi Ran, Louzoun Yoram
Abstract excerpt
MOTIVATION: Viruses employ various means to evade immune detection. One common evasion strategy is the removal of CD8+cytotoxic T-lymphocyte epitopes. We here use a combination of multiple bioinformatic tools and large amount of genomic data to compute the epitope repertoire presented by over 130...
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