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Article

A bioinformatics pipeline for the analyses of viral escape dynamics and host immune responses during an infection.

BioMed research international - 1 Jan 2014

Leung Preston, Bull Rowena, Lloyd Andrew, Luciani Fabio

Abstract excerpt

Rapidly mutating viruses, such as hepatitis C virus (HCV) and HIV, have adopted evolutionary strategies that allow escape from the host immune response via genomic mutations. Recent advances in high-throughput sequencing are reshaping the field of immuno-virology of viral infections, as these allow fast and cheap generation of genomic data. However, due to the large volumes of data generated, a thorough...

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Identifiers

PMID: 25013771
DOI: 10.1155/2014/264519
PMCID: PMC4072169

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