Article
PTPmu signaling via PKCdelta is instructive for retinal ganglion cell guidance.
Molecular and cellular neurosciences - 1 Apr 2004
Ensslen Sonya E, Brady-Kalnay Susann M
Abstract excerpt
The receptor protein tyrosine phosphatase (RPTP) PTPmu mediates distinct cellular responses in nasal and temporal retinal ganglion cell (RGC) axons. PTPmu is permissive for nasal RGC neurite outgrowth and inhibitory to temporal RGCs. In addition, PTPmu causes preferential temporal growth cone collapse. Previous studies demonstrated that PTPmu associates with the scaffolding protein RACK1 and the protein kinase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
