Article
Cell-type specific roles for PTEN in establishing a functional retinal architecture.
PloS one - 1 Jan 2012
Cantrup Robert, Dixit Rajiv, Palmesino Elena, Bonfield Stephan, Shaker Tarek, Tachibana Nobuhiko, Zinyk Dawn, Dalesman Sarah, Yamakawa Kazuhiro, Stell William K, Wong Rachel O, Reese Benjamin E, Kania Artur, Sauvé Yves, Schuurmans Carol
Abstract excerpt
BACKGROUND: The retina has a unique three-dimensional architecture, the precise organization of which allows for complete sampling of the visual field. Along the radial or apicobasal axis, retinal neurons and their dendritic and axonal arbors are segregated into layers, while perpendicular to this axis, in the tangential plane, four of the six neuronal types form patterned cellular arrays, or mosaics. Currently,...
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