Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A relative signalling model for the formation of a topographic neural map.

Nature - 14 Oct 2004

Reber Michaël, Burrola Patrick, Lemke Greg

Abstract excerpt

The highly ordered wiring of retinal ganglion cell (RGC) neurons in the eye to their synaptic targets in the superior colliculus of the midbrain has long served as the dominant experimental system for the analysis of topographic neural maps. Here we describe a quantitative model for the development of one arm of this map--the wiring of the nasal-temporal axis of the retina to the caudal-rostral axis of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Retinal Ganglion Cells
Share to RNA, Messenger
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Models, Neurological

Share to Neural Pathways

Share to Signal Transduction

Share to Superior Colliculi

Source

Identifiers

PMID: 15483613
DOI: 10.1038/nature02957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A relative signalling model for the formation of a topographic neural map.PMID 15483613Read ↗

New model of retinocollicular mapping predicts the mechanisms of axonal competition and explains the role of reverse molecular signaling during development.Semantic proximity Read ↗

Quantitative assessment of computational models for retinotopic map formation.Semantic proximity Read ↗

Modeling development in retinal afferents: retinotopy, segregation, and ephrinA/EphA mutants.Semantic proximity Read ↗

Multiple EphB receptors mediate dorsal-ventral retinotopic mapping via similar bi-functional responses to ephrin-B1.Semantic proximity Read ↗

On the Importance of Countergradients for the Development of Retinotopy: Insights from a Generalised Gierer Model.Semantic proximity Read ↗

Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse.Semantic proximity Read ↗

Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.Semantic proximity Read ↗

Ephrin-As are required for the topographic mapping but not laminar choice of physiologically distinct RGC types.Semantic proximity Read ↗

Target recognition and visual maps in the thalamus of achiasmatic dogs.Semantic proximity Read ↗

Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularitySemantic proximity Read ↗

Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse.Semantic proximity Read ↗

Region-specific Brain Targets Drive Circuit Formation and Maturation of Human Retinal Ganglion CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.