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Article

Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data.

American journal of human genetics - 1 May 2004

Morris A P, Whittaker J C, Balding D J

Abstract excerpt

We present the results of a simulation study that indicate that true haplotypes at multiple, tightly linked loci often provide little extra information for linkage-disequilibrium fine mapping, compared with the information provided by corresponding genotypes, provided that an appropriate statisti...

Topics

Algorithms
Chromosome Mapping
Computer Simulation
Genetic Markers
Genotype
Haplotypes
Humans
Linkage Disequilibrium
Models, Genetic
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15077198
DOI: 10.1086/420773
PMCID: PMC1181987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15077198-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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