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Article

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes.

Genetic epidemiology - 1 Dec 2010

Li Yun, Willer Cristen J, Ding Jun, Scheet Paul, Abecasis Gonçalo R

Abstract excerpt

Genome-wide association studies (GWAS) can identify common alleles that contribute to complex disease susceptibility. Despite the large number of SNPs assessed in each study, the effects of most common SNPs must be evaluated indirectly using either genotyped markers or haplotypes thereof as proxies. We have previously implemented a computationally efficient Markov Chain framework for genotype imputation and...

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Identifiers

PMID: 21058334
DOI: 10.1002/gepi.20533
PMCID: PMC3175618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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