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Article

Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering.

American journal of human genetics - 1 Nov 2007

Browning Sharon R, Browning Brian L

Abstract excerpt

Whole-genome association studies present many new statistical and computational challenges due to the large quantity of data obtained. One of these challenges is haplotype inference; methods for haplotype inference designed for small data sets from candidate-gene studies do not scale well to the large number of individuals genotyped in whole-genome association studies. We present a new method and software for...

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Identifiers

PMID: 17924348
DOI: 10.1086/521987
PMCID: PMC2265661

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