Article
Screening for dysplasia and TP53 mutations in closed rectal stumps of patients with ulcerative colitis or Crohn disease.
Scandinavian journal of gastroenterology - 1 Mar 2004
Winther K V, Bruun E, Federspiel B, Guldberg P, Binder V, Brynskov J
Abstract excerpt
BACKGROUND: Patients who undergo colectomy due to intractable chronic inflammatory bowel disease (IBD) may keep a closed rectal stump for several years, which may be at increased risk of malignant transformation owing to residual inflammatory activity. We examined a hospital series of patients with ulcerative colitis or Crohn colitis to describe the clinical, endoscopical and histological features of the closed...
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