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Article

Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis.

Digestive diseases and sciences - 1 Aug 2022

Akiyama Shintaro, Ollech Jacob E, Traboulsi Cindy, Rai Victoria, Glick Laura R, Yi Yangtian, Runde Joseph, Olivas Andrea D, Weber Christopher R, Cohen Russell D, Olortegui Kinga B Skowron, Hurst Roger D, Umanskiy Konstantin, Shogan Benjamin D, Rubin Michele A, Dalal Sushila R, Sakuraba Atsushi, Pekow Joel, Chang Eugene B, Hart John, Hyman Neil H, Rubin David T

Abstract excerpt

BACKGROUND: The endoscopic appearance in patients with "pouchitis" after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) can be quite heterogenous. Patients with an endoscopic phenotype resembling Crohn's disease (CD) are at high risk of pouch loss. AIMS: We aimed to assess how the histopathology of colectomy specimens predicts endoscopic pouch phenotypes in UC. METHODS: We retrospectively...

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Identifiers

PMID: 35288827
DOI: 10.1007/s10620-022-07405-y
PMCID: PMC10966959

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