Article
p53 mutation in patients with ulcerative colitis in rectal biopsy.
The Korean journal of internal medicine - 1 Jul 1998
Kim H J, Chang S K
Abstract excerpt
OBJECTIVES: Long standing ulcerative colitis (UC) has been known to be one of the precancerous diseases of colorectal cancer. Although the frequent loss of p53 allele (LOH) and aneuploidy were reported as the molecular events in carcinoma and dysplasia known as the precursor of UC, p53 genetic al...
Topics
- Adolescent
- Adult
- Base Sequence
- Biopsy, Needle
- Child
- Child, Preschool
- Colitis, Ulcerative
- Colonic Neoplasms
- Colonoscopy
- Female
- Humans
- Infant
- Intestinal Mucosa
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Precancerous Conditions