Article
p53 mutation in patients with ulcerative colitis in rectal biopsy.
The Korean journal of internal medicine - 1 Jul 1998
Kim H J, Chang S K
Abstract excerpt
OBJECTIVES: Long standing ulcerative colitis (UC) has been known to be one of the precancerous diseases of colorectal cancer. Although the frequent loss of p53 allele (LOH) and aneuploidy were reported as the molecular events in carcinoma and dysplasia known as the precursor of UC, p53 genetic alteration was not reported in indefinite dysplasia and UC involved mucosa in long standing UC. Therefore, we...
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