Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A unique basal pattern of p53 expression in ulcerative colitis is associated with mutation in the p53 gene.

Histopathology - 1 Nov 2001

Noffsinger A E, Belli J M, Miller M A, Fenoglio-Preiser C M

Abstract excerpt

AIMS: The p53 protein is implicated in the control of cell proliferation, differentiation, and death. As part of a study characterizing p53 alterations in colonic mucosa of patients with ulcerative colitis, we identified a unique pattern of basal p53 immunoreactivity. METHODS AND RESULTS: Tissue samples (n=180) from 42 ulcerative colitis patients were evaluated for p53 alterations by immunohistochemistry, loss of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis, Ulcerative
Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclins

Share to Loss of Heterozygosity

Share to Point Mutation

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins c-mdm2

Source

Identifiers

PMID: 11737306
DOI: 10.1046/j.1365-2559.2001.01274.x

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A unique basal pattern of p53 expression in ulcerative colitis is associated with mutation in the p53 gene.PMID 11737306Read ↗

p53 protein expression in ulcerative colitis-associated colorectal dysplasia and carcinomaSemantic proximity Read ↗

p53 Expression as a Diagnostic Biomarker in Ulcerative Colitis-Associated Cancer.Semantic proximity Read ↗

[Alterations of p53 gene and microsatellite instability in ulcerative colitis and ulcerative colitis-associated colorectal cancer].Semantic proximity Read ↗

Infrequent p53 gene alterations in ulcerative colitis.Semantic proximity Read ↗

Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis.Semantic proximity Read ↗

Mutations of p53 in morphologically non-neoplastic mucosa of long-standing ulcerative colitis.Semantic proximity Read ↗

Usefulness of analysis of p53 alteration and observation of surface microstructure for diagnosis of ulcerative colitis-associated colorectal neoplasia.Semantic proximity Read ↗

Genomic Profiling of Cancerous Areas, Dysplasia, and Background Mucosa in Ulcerative Colitis-associated Colorectal Cancer.Semantic proximity Read ↗

Upregulation of p16(INK4A) and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours.Semantic proximity Read ↗

Barrett's esophagus. The significance of p53 in clinical practice.Semantic proximity Read ↗

Staining patterns of p53 immunohistochemistry and their biological significance in colorectal cancer.Semantic proximity Read ↗

p53 gene mutation and protein accumulation during neoplastic progression in Barrett's esophagus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.