Article
Ulcerative colitis neoplasia is not associated with common inflammatory bowel disease single-nucleotide polymorphisms.
Surgery - 1 Aug 2014
Connelly Tara M, Berg Arthur S, Harris Leonard R, Brinton David L, Hegarty John P, Deiling Sue M, Stewart David B, Koltun Walter A
Abstract excerpt
BACKGROUND: Neoplasia complicating ulcerative colitis (UC-neoplasia) is a problem that is poorly addressed by present surveillance techniques. The association of greater than 300 single nucleotide polymorphisms (SNPs) with inflammatory bowel disease (IBD) suggests the possibility that certain genetic polymorphisms might identify patients with UC destined for malignant degeneration. This present study tested the...
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