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Article

Host factors impacting the innate response in humans to the candidate adjuvants RC529 and monophosphoryl lipid A.

Vaccine - 29 Mar 2004

Tiberio Lorrie, Fletcher Leah, Eldridge John H, Duncan David D

Abstract excerpt

The aim of this study was to determine if certain genotypes might be associated with variable responses to the candidate vaccine adjuvants RC529 and monophosphoryl lipid A (MPL), as well as to bacterial LPS, a structurally similar control stimulus. In this study, the +896 TLR4 polymorphism and selected cytokine polymorphisms were genotyped, and together with the donor sex, these factors were used to model the in...

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Share to Adjuvants, Immunologic
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15063577
DOI: 10.1016/j.vaccine.2003.10.019

Genes

TLR4
MPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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