Article
Sexual dimorphism in innate immunity.
Arthritis and rheumatism - 1 Jan 2002
Moxley George, Posthuma Danielle, Carlson Patricia, Estrada Eloise, Han Jinfeng, Benson Linda L, Neale Michael C
Abstract excerpt
OBJECTIVE: To establish whether variation in innate immunity, as measured by the level of tumor necrosis factor (TNF) in lipopolysaccharide (LPS)-stimulated whole-blood culture, is related to sex or HLA. METHODS: Normal volunteers (72 women, 159 men) completed questionnaires and donated peripheral blood specimens. Blood samples were exposed to LPS in a 4-hour in vitro culture, and supernatants were then tested by...
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