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Article

The role of Toll-like receptor 4 polymorphisms in vaccine immune response.

The pharmacogenomics journal - 1 Feb 2016

Pellegrino P, Falvella F S, Cheli S, Perrotta C, Clementi E, Radice S

Abstract excerpt

Toll-like receptors (TLRs) are a class of pattern recognition receptors that are deputed to recognise a range of molecular structures in pathogens. One of the most studied members of this family is the TLR4, which is essential for the signalling of lipopolysaccharide. The gene encoding for TLR4 is highly polymorphic and this genetic variability may explain in part the interindividual variability observed in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25823688
DOI: 10.1038/tpj.2015.21

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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