Article
High frequency of G/C transversion on p53 gene alterations in breast cancers from Taiwan.
Cancer letters - 15 Apr 2004
Chen Fang-Ming, Hou Ming-Feng, Wang Jaw-Yuan, Chen Tsung-chi, Chen David C P, Huang Sung-Yu, Chung Yi-Shu, Lin Shiu-Ru
Abstract excerpt
p53 gene mutation is a very frequent event in many human cancers and is associated with a poor clinical outcome in breast cancer patients. Analysis of p53 gene mutations can also provide clues to the etiology of tumor formation. The present study was conducted to investigate the p53 mutations in patients with breast cancer from Taiwan. Tumor samples from 119 patients undergoing mastectomy for breast cancer were...
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