Mutations of p53 gene in breast cancer in the Egyptian province of Dakahliya.

doi:10.1177/1078155209356130

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Article

Mutations of p53 gene in breast cancer in the Egyptian province of Dakahliya.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners - 1 Jun 2011

El-Ghannam Doaa M, Arafa Mohammad, Badrawy Tarek

Abstract excerpt

BACKGROUND: Breast cancer is the most common malignancy among females worldwide. Molecular analysis of p53 is likely to have value in diagnosis, prognosis, and treatment of breast cancer. OBJECTIVE: To study the frequency and spectrum of p53 gene mutations in breast cancer patients residing Al Dakahliya district in the north of Egypt. MATERIALS AND METHODS: Thirty patients with cancer breast as well as 10...

Topics

Adult
Breast Neoplasms
Carcinoma
Codon, Nonsense
DNA Mutational Analysis
Egypt
Exons
Female
Frameshift Mutation
Genes, p53
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Middle Aged

Mutation

Mutation, Missense

Neoplasm Invasiveness

Neoplasm Staging

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 20015931
DOI: 10.1177/1078155209356130

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