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Article

Frequency of spontaneous p53 mutations (CpG site) in breast cancer in Japan.

Breast cancer research and treatment - 1 Sept 1993

Sasa M, Kondo K, Komaki K, Uyama T, Morimoto T, Monden Y

Abstract excerpt

Sixty-five tumors of invasive ductal carcinoma of the breast were examined for p53 alteration by the reverse transcription-polymerase chain reaction-single strand conformation polymorphism (RT-PCR-SSCP) method and sequencing analysis. In total, 16 samples (24.6%) showed p53 gene alteration. Sixteen of these alterations were evaluated by sequencing analysis, and 15 showed missense point mutations while one showed...

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PMID: 8312582
DOI: 10.1007/BF00665694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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