Frequency of spontaneous p53 mutations (CpG site) in breast cancer in Japan.

doi:10.1007/BF00665694

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Article

Frequency of spontaneous p53 mutations (CpG site) in breast cancer in Japan.

Breast cancer research and treatment - 1 Sept 1993

Sasa M, Kondo K, Komaki K, Uyama T, Morimoto T, Monden Y

Abstract excerpt

Sixty-five tumors of invasive ductal carcinoma of the breast were examined for p53 alteration by the reverse transcription-polymerase chain reaction-single strand conformation polymorphism (RT-PCR-SSCP) method and sequencing analysis. In total, 16 samples (24.6%) showed p53 gene alteration. Sixte...

Topics

Adult
Aged
Base Sequence
Breast Neoplasms
Female
Genes, p53
Humans
Middle Aged
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

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