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Article

Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors.

Brain research. Molecular brain research - 7 Apr 2004

Thompson Charles, Gary Devin, Mattson Mark, Mackenzie Alex, Robertson George S

Abstract excerpt

Mice that lack tumor necrosis factor-alpha (TNF) receptors are more susceptible than wild-type animals to brain injury produced by kainic acid or transient focal ischemia suggesting that the rapid production of TNF that occurs after these insults serves a neuroprotective role. The mechanisms by which TNF reduces neuronal loss after brain injury may involve the up-regulation of proteins that maintain calcium...

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Source

Identifiers

PMID: 15046874
DOI: 10.1016/j.molbrainres.2004.01.009

Genes

TNF
NAIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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