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Article

Involvement of tumor necrosis factor alpha in hippocampal development and function.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jan 2004

Golan H, Levav T, Mendelsohn A, Huleihel M

Abstract excerpt

Tumor necrosis factor alpha (TNFalpha) is a cytokine produced mainly by cells of the immune system. It is also expressed by brain neurons and glia. The physiological role of TNFalpha in the brain is not yet fully clear. Using TNFalpha-deficient mice, we have examined its role in hippocampal development and function. We report here that TNFalpha is involved in the regulation of morphological development in the...

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Source

Identifiers

PMID: 14654461
DOI: 10.1093/cercor/bhg108

Genes

NGF
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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