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Article

A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.

The Journal of biological chemistry - 3 Dec 2004

Okuda Masahiko, Tanaka Aki, Arai Yoko, Satoh Manami, Okamura Hideyasu, Nagadoi Aritaka, Hanaoka Fumio, Ohkuma Yoshiaki, Nishimura Yoshifumi

Abstract excerpt

The zinc finger domain in the large subunit of TFIIE (TFIIEalpha) is phylogenetically conserved and is essential for transcription. Here, we determined the solution structure of this domain by using NMR. It consisted of one alpha-helix and five beta-strands, showing novel features distinct from previously determined zinc-binding structures. We created point mutants of TFIIEalpha in this domain and examined their...

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Source

Identifiers

PMID: 15385556
DOI: 10.1074/jbc.M404722200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.PMID 15385556Read ↗

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