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Article

Assembly of human small nuclear RNA gene-specific transcription factor IIIB complex de novo on and off promoter.

The Journal of biological chemistry - 26 Jul 2002

Cabart Pavel, Murphy Shona

Abstract excerpt

In humans, transcription factor IIIB (TFIIIB)-alpha governs basal transcription from small nuclear RNA genes by RNA polymerase III (pol III). One of the components of this complex, BRFU/TFIIIB50, is specific for these promoters, whereas TATA-binding protein (TBP) and hB" are required for pol III transcription from both gene external and internal promoters. We show that hB" is specifically recruited to a...

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Identifiers

PMID: 12016223
DOI: 10.1074/jbc.M203119200

Genes

TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Assembly of human small nuclear RNA gene-specific transcription factor IIIB complex de novo on and off promoter.PMID 12016223Read ↗

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