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Article

Mutations in DNA mismatch repair genes: implications for DNA damage signaling and drug sensitivity (review).

International journal of oncology - 1 Apr 2004

Fedier Andre, Fink Daniel

Abstract excerpt

The DNA mismatch repair (MMR) system functions in the elimination of biosynthetic errors that arise during DNA replication, in DNA damage surveillance, and in the prevention of recombination between non-identical sequences. It therefore substantially contributes to the maintenance of genome integrity. It is thus not surprising that loss of MMR function may lead to cancer. Inherited defects due to germline...

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PMID: 15010846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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