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Article

DNA mismatch repair proteins: scientific update and practical guide.

Journal of clinical pathology - 1 Apr 2021

Bateman Adrian C

Abstract excerpt

DNA mismatch repair (MMR) proteins are essential for the recognition and correction of sporadic genetic mutations that occur during DNA replication. Deficient MMR function (dMMR) leads to an increased risk of development of neoplasia. Identification of dMMR within tumours can suggest a high chance of the inherited cancer condition Lynch syndrome and predicts poor clinical response to certain conventional...

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Identifiers

PMID: 33597222
DOI: 10.1136/jclinpath-2020-207281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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