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Article

Genome screen for a combined bone phenotype using principal component analysis: the Framingham study.

Bone - 1 Mar 2004

Karasik D, Cupples L A, Hannan M T, Kiel D P

Abstract excerpt

Genetic factors substantially contribute to variation in bone mass. There is a controversy as to whether shared genetic factors exist for bone mass at different sites. We hypothesize that using a composite phenotypic score of several correlated bone mass measures may provide complementary results for linkage studies. In the members of 323 pedigrees from the Framingham Osteoporosis Study, bone mineral density...

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Identifiers

PMID: 15003802
DOI: 10.1016/j.bone.2003.11.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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