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Article

Genome-wide association with bone mass and geometry in the Framingham Heart Study.

BMC medical genetics - 19 Sept 2007

Kiel Douglas P, Demissie Serkalem, Dupuis Josée, Lunetta Kathryn L, Murabito Joanne M, Karasik David

Abstract excerpt

BACKGROUND: Osteoporosis is characterized by low bone mass and compromised bone structure, heritable traits that contribute to fracture risk. There have been no genome-wide association and linkage studies for these traits using high-density genotyping platforms. METHODS: We used the Affymetrix 100K SNP GeneChip marker set in the Framingham Heart Study (FHS) to examine genetic associations with ten primary...

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Source

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Identifiers

PMID: 17903296
DOI: 10.1186/1471-2350-8-S1-S14
PMCID: PMC1995606

Genes

ANKH
ESR1
LRP5
MAF
MTHFR
PPARG
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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