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Article

Evidence for major pleiotropic effects on bone size variation from a principal component analysis of 451 Caucasian families.

Acta pharmacologica Sinica - 1 Jun 2008

Tan Li-jun, Liu Yao-zhong, Xiao Peng, Yang Fang, Tang Zi-hui, Liu Peng-yuan, Recker Robert R, Deng Hong-wen

Abstract excerpt

AIM: To identify pleiotropic quantitative trait loci (QTL) influencing bone size (BS) at different skeletal sites in Caucasians. METHODS: In a sample containing 3899 Caucasians from 451 pedigrees, 410 microsatellite markers spaced approximately 8.9 cM apart across the human genome were genotyped. Phenotypical and genetic correlations of BS at lumbar spine, hip (femoral neck, trochanter, and intertrochanter...

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PMID: 18501122
DOI: 10.1111/j.1745-7254.2008.00806.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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