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Article

Univariate and bivariate variance component linkage analysis of a whole-genome scan for loci contributing to bone mineral density.

European journal of human genetics : EJHG - 1 Jun 2005

Devoto Marcella, Spotila Loretta D, Stabley Deborah L, Wharton Gina N, Rydbeck Halfdan, Korkko Jarmo, Kosich Richard, Prockop Darwin, Tenenhouse Alan, Sol-Church Katia

Abstract excerpt

Osteoporosis is a common condition characterized by reduced skeletal strength and increased susceptibility to fracture. The single major risk factor for osteoporosis is low bone mineral density (BMD) and strong evidence exists that genetic factors are in part responsible for an individual's BMD. A cohort of 40 multiplex Caucasian families selected through a proband with osteoporosis was genotyped for...

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PMID: 15827564
DOI: 10.1038/sj.ejhg.5201411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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