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Article

Codon usage between genomes is constrained by genome-wide mutational processes.

Proceedings of the National Academy of Sciences of the United States of America - 9 Mar 2004

Chen Swaine L, Lee William, Hottes Alison K, Shapiro Lucy, McAdams Harley H

Abstract excerpt

Analysis of genome-wide codon bias shows that only two parameters effectively differentiate the genome-wide codon bias of 100 eubacterial and archaeal organisms. The first parameter correlates with genome GC content, and the second parameter correlates with context-dependent nucleotide bias. Both...

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PMID: 14990797
DOI: 10.1073/pnas.0307827100
PMCID: PMC373487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14990797-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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