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Article

Variation in global codon usage bias among prokaryotic organisms is associated with their lifestyles.

Genome biology - 27 Oct 2011

Botzman Maya, Margalit Hanah

Abstract excerpt

BACKGROUND: It is widely acknowledged that synonymous codons are used unevenly among genes in a genome. In organisms under translational selection, genes encoding highly expressed proteins are enriched with specific codons. This phenomenon, termed codon usage bias, is common to many organisms and has been recognized as influencing cellular fitness. This suggests that the global extent of codon usage bias of an...

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Identifiers

PMID: 22032172
DOI: 10.1186/gb-2011-12-10-r109
PMCID: PMC3333779

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