Article
Multiplicative versus additive selection in relation to genome evolution: a simulation study.
Genetical research - 1 Oct 2001
Piganeau G, Westrelin R, Tourancheau B, Gautier C
Abstract excerpt
The evolution of molecular quantitative traits, such as codon usage bias or base frequencies, can be explained as the result of mutational biases alone, or as the result of mutation and selection. Whereas mutation models can be investigated easily, realistic modelling of selection-directed genome evolution is analytically intractable, and numerical calculations require substantial computer resources. We...
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