Article
Implication of proteins containing tetratricopeptide repeats in conditional virulence phenotypes of Legionella pneumophila.
Journal of bacteriology - 1 Jul 2012
Bandyopadhyay Purnima, Sumer Eren U, Jayakumar Deepak, Liu Shuqing, Xiao Huifang, Steinman Howard M
Abstract excerpt
Legionella pneumophila, the causative agent of Legionnaires' disease, is a ubiquitous freshwater bacterium whose virulence phenotypes require a type IV secretion system (T4SS). L. pneumophila strain JR32 contains two virulence-associated T4SSs, the Dot/Icm and Lvh T4SSs. Defective entry and phagosome acidification phenotypes of dot/icm mutants are conditional and reversed by incubating broth-grown...
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