Article
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.
Diabetes - 1 Mar 2004
Silander Kaisa, Scott Laura J, Valle Timo T, Mohlke Karen L, Stringham Heather M, Wiles Kerry R, Duren William L, Doheny Kimberly F, Pugh Elizabeth W, Chines Peter, Narisu Narisu, White Peggy P, Fingerlin Tasha E, Jackson Anne U, Li Chun, Ghosh Soumitra, Magnuson Victoria L, Colby Kimberly, Erdos Michael R, Hill Jason E, Hollstein Pablo, Humphreys Kathleen M, Kasad Roshni A, Lambert Jessica, Lazaridis Konstantinos N, Lin George, Morales-Mena Anabelle, Patzkowski Kristin, Pfahl Carrie, Porter Rachel, Rha David, Segal Leonid, Suh Yong D, Tovar Jason, Unni Arun, Welch Christian, Douglas Julie A, Epstein Michael P, Hauser Elizabeth R, Hagopian William, Buchanan Thomas A, Watanabe Richard M, Bergman Richard N, Tuomilehto Jaakko, Collins Francis S, Boehnke Michael
Abstract excerpt
The aim of the Finland-United States Investigation of NIDDM Genetics (FUSION) study is to identify genes that predispose to type 2 diabetes or are responsible for variability in diabetes-related traits via a positional cloning and positional candidate gene approach. In a previously published genome-wide scan of 478 Finnish affected sibling pair (ASP) families (FUSION 1), the strongest linkage results were on...
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