Article
Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.
Diabetes - 1 Apr 2002
Mori Yasumichi, Otabe Shuichi, Dina Christian, Yasuda Kazuki, Populaire Céline, Lecoeur Cécile, Vatin Vincent, Durand Emmanuelle, Hara Kazuo, Okada Terumasa, Tobe Kazuyuki, Boutin Philippe, Kadowaki Takashi, Froguel Philippe
Abstract excerpt
The genetic background that predisposes the Japanese population to type 2 diabetes is largely unknown. Therefore, we conducted a 10-cM genome-wide scan for type 2 diabetes traits in the 359 affected individuals from 159 families, yielding 224 affected sib-pairs of Japanese origin. Nonparametric m...
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