Article
Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese.
Journal of human genetics - 1 Jan 2004
Nawata Hajime, Shirasawa Senji, Nakashima Naoki, Araki Eiichi, Hashiguchi Jun, Miyake Seibei, Yamauchi Teruaki, Hamaguchi Kazuyuki, Yoshimatsu Hironobu, Takeda Haruo, Fukushima Hideo, Sasahara Takayuki, Yamaguchi Kohei, Sonoda Noriyuki, Sonoda Tomoko, Matsumoto Masahiro, Tanaka Yoshiya, Sugimoto Hidekatsu, Tsubouchi Hirotaka, Inoguchi Toyoshi, Yanase Toshihiko, Wake Nakayasu, Narazaki Kenziro, Eto Takashi, Umeda Fumio, Nakazaki Mitsuhiro, Ono Junko, Asano Takashi, Ito Yasuko, Akazawa Shoichi, Hazegawa Iwaho, Takasu Nobuyuki, Shinohara Moritsugu, Nishikawa Takeshi, Nagafuchi Seiho, Okeda Toshimitsu, Eguchi Katsumi, Iwase Masanori, Ishikawa Mayuko, Aoki Masayuki, Keicho Naoto, Kato Norihiro, Yasuda Kazuki, Yamamoto Ken, Sasazuki Takehiko
Abstract excerpt
Type 2 diabetes mellitus is a heterogeneous disorder, and the development of type 2 diabetes mellitus is associated with both insulin secretion defect and insulin resistance. The primary metabolic defect leading to type 2 diabetes mellitus has been thought to be varied among populations, especially in Japanese and Caucasians. Here, we have done the genome-wide scan for type 2 diabetes mellitus using 102 affected...
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