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Article

Analysis of gene x environment interactions in sibships using mixed models.

BMC genetics - 31 Dec 2003

Barnholtz-Sloan Jill S, Poisson Laila M, Coon Steven W, Chase Gary A, Rybicki Benjamin A

Abstract excerpt

BACKGROUND: Gene x environment models are widely used to assess genetic and environmental risks and their association with a phenotype of interest for many complex diseases. Mixed generalized linear models were used to assess gene x environment interactions with respect to systolic blood pressure on sibships adjusting for repeated measures and hierarchical nesting structures. A data set containing 410 sibships...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14975086
DOI: 10.1186/1471-2156-4-S1-S18
PMCID: PMC1866452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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