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Article

Three Approaches to Modeling Gene-Environment Interactions in Longitudinal Family Data: Gene-Smoking Interactions in Blood Pressure.

Genetic epidemiology - 1 Jan 2016

Basson Jacob, Sung Yun Ju, de las Fuentes Lisa, Schwander Karen L, Vazquez Ana, Rao Dabeeru C

Abstract excerpt

Blood pressure (BP) has been shown to be substantially heritable, yet identified genetic variants explain only a small fraction of the heritability. Gene-smoking interactions have detected novel BP loci in cross-sectional family data. Longitudinal family data are available and have additional promise to identify BP loci. However, this type of data presents unique analysis challenges. Although several methods for...

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Source

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Identifiers

PMID: 26625943
DOI: 10.1002/gepi.21941
PMCID: PMC4867544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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