Article

Review: Population Structure in Genetic Studies: Confounding Factors and Mixed Models

2016-12-07

Abstract excerpt

A genome-wide association study (GWAS) seeks to identify genetic variants that contribute to the development and progression of a specific disease. Over the past 10 years, new approaches using mixed models have emerged to mitigate the deleterious effects of population structure and relatedness in association studies. However, developing GWAS techniques to effectively test for association while correcting for popul...

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Literature Corpus work: 9aca02cf-aa06-5b7d-a50a-a7bf192505f5
DOI: 10.1101/092106

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