Article
Joint genetic analysis using variant sets reveals polygenic gene-context interactions
2016-12-31
Abstract excerpt
Joint genetic models for multiple traits have helped to enhance association analyses. Most existing multi-trait models have been designed to increase power for detecting associations, whereas the analysis of interactions has received considerably less attention. Here, we propose iSet, a method based on linear mixed models to test for interactions between sets of variants and environmental states or other contexts....
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Identifiers and source
- Literature Corpus work
- 62251b50-ea57-5833-badb-c64ddf42385f
- DOI
- 10.1101/097477