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Article

CLCA2 tumour suppressor gene in 1p31 is epigenetically regulated in breast cancer.

Oncogene - 19 Feb 2004

Li Xiurong, Cowell John K, Sossey-Alaoui Khalid

Abstract excerpt

The calcium-activated chloride channel gene family is clustered in the 1p31 region, which is frequently deleted in sporadic breast cancer. Recent studies have indicated the association of the second member of this gene family (CLCA2) with the development of breast cancer and metastasis. We have now shown the absence of expression of CLCA2 in several breast cancer tumours and cell lines, which confirms the results...

Read the complete abstract on PubMed

Topics

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Share to Breast Neoplasms
Share to Chloride Channels
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

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Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 14973555
DOI: 10.1038/sj.onc.1207249

Genes

CLCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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