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Article

Tumorigenicity of human breast cancer is associated with loss of the Ca2+-activated chloride channel CLCA2.

Cancer research - 1 Nov 1999

Gruber A D, Pauli B U

Abstract excerpt

The human Ca2+-activated chloride channel-2 (CLCA2) is expressed in normal breast epithelium but not in breast tumors of different stages of progression. Northern analysis of nontransformed and transformed breast epithelial cell lines revealed CLCA2 expression in the nontransformed cell line MCF10A and the nontumorigenic cell line MDA-MB-453, whereas all tumorigenic cell lines were negative (MDA-MB-231,...

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Source

Identifiers

PMID: 10554024

Genes

CLCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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