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Article

CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk.

International journal of cancer - 10 Mar 2002

Lei Haixin, Sjöberg-Margolin Sara, Salahshor Sima, Werelius Barbro, Jandáková Eva, Hemminki Kari, Lindblom Annika, Vorechovský Igor

Abstract excerpt

Mutations and diminished expression of the E-cadherin gene (CDH1) have been identified in a number of epithelial malignancies. Although somatic CDH1 mutations were detected in lobular breast cancer with a frequency ranging from 10-56%, CDH1 alterations in more frequent ductal tumors appear to be rare. Here we have analyzed the coding region of CDH1 for mutations using denaturing high performance liquid...

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Source

Identifiers

PMID: 11857408
DOI: 10.1002/ijc.10176

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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