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Article

Non-existence of caveolin-1 gene mutations in human breast cancer.

Breast cancer research and treatment - 1 Jan 2012

Patani Neill, Lambros Maryou B, Natrajan Rachael, Dedes Konstantin J, Geyer Felipe C, Ward Eric, Martin Lesley-Ann, Dowsett Mitch, Reis-Filho Jorge S

Abstract excerpt

Caveolin-1 is the principal constituent protein of caveolae, which are specialised plasma membrane invaginations with diverse biological roles. Caveolin-1 is suggested to have tumour suppressive functions and CAV1 gene mutations have been reported in 20% of breast cancers. The aim of the present study was to evaluate the frequency of CAV1 mutations in a large cohort of optimally accrued breast cancers. Two...

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Source

Identifiers

PMID: 21909981
DOI: 10.1007/s10549-011-1761-2

Genes

CAV1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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