Article
Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.
The American journal of pathology - 1 Jun 2006
Li Tianhong, Sotgia Federica, Vuolo Magalis A, Li Maomi, Yang Wan Cai, Pestell Richard G, Sparano Joseph A, Lisanti Michael P
Abstract excerpt
A Japanese study reported that up to 16% of breast cancer samples harbor a sporadic mutation within the human Cav-1 gene, namely P132L. To date, however, no studies have examined the United States' population. Here, we developed a novel allele-specific real-time PCR assay to detect the Cav-1 P132...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.